Jigar Patel

Previous positions

  • Software Engineering Intern at SMEDIX Inc
  • Bioinformatics Scientist at University of California, Los Angeles

Education

University of California, San Diego, Bachelor of Science – BS, Bioinformatics

 

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Background

Experience

  • Software Engineering Intern

    SMEDIX Inc

    February 2019 – July 2019(5 months)

    • Developed an application in Python using Wooey, Django and Celery to automatically generate internal documentation • Dockerized variant caller pipeline for efficient version control

  • Bioinformatics Scientist

    University of California, Los Angeles

    June 2017 – August 2017(2 months)Institute for Quantitative and Computational Biology

    Used and developed Bioinformatics tools to study differential Analysis of H4K20 Methylation Marks in Proliferating and Contact Inhibited Human Dermal Fibroblasts. Our findings raise the possibility that the role of Suv4-20h2, a methyltransferase that generates H4K20me3, in proliferation is mediated through effects on the expression of zinc finger proteins.

  • Assist researchers at Gleeson Lab analyze exome and genome sequences through Genome Analysis Toolkit (GATK) pipeline to discover potential genes that are related to neurological disease. Program used: – Picard – Samtools – Bowtie Skills Developed: – Ability to work in a command line environment. – Programming in Python – Strong understanding of good software development practices – Stronger understanding of genetics

  • Undergraduate Researcher

    La Jolla Institute for Allergy and Immunology

    June 2016 – September 2016(3 months)Hogan/Rao Lab

    Nuclear factor of activated T-cells (NFAT) protein have an important role in the development and functioning of immune system. NFAT proteins have weak DNA-binding capacity. Therefore, it binds with other cofactors for stability. NFAT and Fos-Jun are two transcription factor that binds together on DNA. By using this as our test case, we were trying to discover other partners of NFAT using APEX tag technology. APEX (ascorbate peroxidase) functions as an electron microscopy (EM) tag and labeling enzyme for neighbor proteins. Here is a very interesting paper on APEX tag technology: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916822/pdf/nihms-552295.pdf Skills and Techniques Developed: – DNA Extraction – Agarose Gel Electrophoresis – Northern/Western Blot – PCR – Protein Tag and many more.

Education

  • University of California, San Diego

    Bachelor of Science – BS, Bioinformatics

    2014 – 2018

    Activities and Societies

    Undergraduate Bioinformatics Club (Council Representative), English-In-Action (Tutor), Academic Integrity Office (Peer Educator)

  • Hawthorne High School

    High School Diploma

    2010 – 2014

    Activities and Societies

    Helping Hands, National Honor Society, Key Club (Kiwanis), California Federation Scholarship

Languages

  • Gujarati

    Native or bilingual proficiency

  • English

    Native or bilingual proficiency

  • Hindi

    Limited working proficiency

Projects

  • TErex1.0

    Objective Given an input query, TErex1.0 identifies all the transposable elements within it through an alignment method that uses the Dfam database. Significance Transposon annotation is an important tool because of the significance of transposable elements. Transposons are elements that move, or “jump around,” from one position to another within the genome, and they’re found abundantly in nearly all prokaryotes and eukaryotes. Consequently, transposable elements can lead to mutations, and recently, they’ve found a few transposons in cancer-related genes, indicating disease development. Because of their ability to “jump around,” transposons drive genomic evolution and gene regulation by enabling translocation, exon shuffling, and increasing diversity, among its many effects. Their genetic influence makes transposons important elements to identify and study.

    Team Members (1):
    • Jigar Patel
  • Kumas

    Finalist for UC Health Hack. Dementia is a condition associated with impairments of memory, communication and cognition abilities. It is caused as a result of damage to brain cells. Current statistics predict that at least one in three seniors will die as a result of Alzheimer’s disease or some other form of dementia. Memory loss, communication problems, mood swings and difficulty completing familiar tasks are usual symptoms. As dementia is caused by brain cell death, there is no cure for degenerative dementia. However, there are treatments to alleviate and improve the symptoms associated with the condition. The physicians have to rely on the caretakers or the patients to understand and assess the patient’s condition as there is no current method to obtain the information at the time of the episode. Our programs aims to bridge the gap between the doctor patient interaction by obtaining quantitative data from the patient through a series of games and questions.

    Team Members (2):
    • Jigar Patel,
    • Payal Ramchandani
  • Illumina Outreach

    Team Members (1):
    • Jigar Patel

Skills & Expertise

  • Event Planning
  • Statistics
  • Algorithms
  • Pipelines
  • Leadership
  • Computer-Aided Design (CAD)
  • Bioinformatics
  • Data Analysis
  • Dance
  • Analytical Skills
  • Cassandra
  • GATK
  • Project Management
  • SDSC
  • SolidWorks
  • Microsoft Excel
  • Public Speaking
  • Natural Language Processing (NLP)
  • Python
  • Microsoft Office
  • Machine Learning
  • After Effects
  • PowerPoint
  • Research
  • Management
  • Linux
  • Biotechnology
  • Teamwork
  • Object-Oriented Programming (OOP)
  • Docker
  • Genetic Algorithms
  • MySQL
  • C++
  • JAVA
  • HTML
  • Microsoft Word
  • DNA
  • Bash
  • R
  • Programming
  • Adobe Photoshop
  • Cloud Computing
  • Genetics
  • Software Development

Courses

University of California, San Diego

  • Metabolic Biochemistry (BIBC 102)
  • Fluency/Information Technology (CSE 3)
  • Culture, Art & Technology I(CAT 1)
  • Big Data Analysis in Computational Molecular Biology(SIO 190/242C)
  • Diversity, Equity, and Inclusion in Relation to Human Bio (BILD 60)
  • General Chemistry III (CHEM 6C)
  • Molecular Biology(BIMM 100)
  • Calculus/Science & Engineering (MATH 20B)
  • The Cell(BILD 1)
  • Culture, Art & Technology III (CAT 3)
  • General Chemistry Laboratory (CHEM 7L)
  • Personal Ethics at Work (MGT 16)
  • Basic Data Structures and Object-Oriented Design(CSE 12)
  • Introduction to Cognitive Science (COGS 1)
  • Organic Chemistry II(CHEM 140B)
  • Calculus/Science & Engineering (MATH 20C)
  • Molecular Biology([BIMM 100])
  • Intro/Computer Sci: Java (I) (CSE 8A)
  • Intro/Computer Sci. Java (II)(CSE 8B)
  • General Chemistry I(CHEM 6A)
  • Physics-Mechanics(PHYS 2A)
  • Physics-Mechanics(PHYS 2A)
  • Multicellular Life (BILD 2)
  • Organic Chemistry I(CHEM 140A)
  • Physics-Electricity and Magnetism (PHYS 2B)
  • Advanced Data Structures(CSE 100)
  • Computer Science & Engineering: Issues/Bioinformatics(CSE 191)
  • Biology Meets Computing (CSE 180)
  • General Chemistry II (CHEM 6B)
  • Calculus/Science & Engineering(MATH 20A)
  • Gospel Choir (MUSIC 95G)

Independent Coursework

  • Math/Algorithms & Systems Analysis (CSE 21)
  • Culture, Art & Technology II (CAT 2)

Honors & Awards

  • Academic Integrity Award

    Academic Intergrity Office

    April 2016

  • Academic Scholarship

    Sandpipers

    June 2013

    Full ride to four-year university.

  • Student of the Year

    Cal Lutheran University

    June 2014

Organizations

  • English-In-Action

    Tutor

    November 2016 – Present

  • Undergraduate Bioinformatics Club

    Vice President Internal

    July 2016 – Present

    Previously position held: July 2016 – June 2017 : Council Representative September 2016 – July 2016: General Member

  • Academic Integrity Office

    Peer Educator

    November 2016 – Present